Apparatus and method for acoustic heat generation and hyperthermia

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United States of America Patent

PATENT NO 5501655
SERIAL NO

08275809

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Abstract

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An ultrasound hyperthermia applicator suitable for medical hyperthermia treatment, and method for using the same, includes two ultrasound sources producing focused ultrasound beams of frequencies f.sub.0 and f.sub.1. An aiming device directs the two ultrasound beams so that they cross each other confocally at the target. A controller activates the two ultrasound sources so that the target is simultaneously irradiated by the two focused ultrasound beams. The two ultrasound sources provide acoustic energy sufficient to cause significant intermodulation products to be produced at the target due to the interaction of the two ultrasound beams. The intermodulation products are absorbed by the target to enhance heating of the target. In preferred embodiments the ultrasound sources include pair of signal generator for producing gated ultrasound output signals driving single crystal ultrasound transducers. In other embodiments the ultrasound sources include a pair of phased array ultrasound transducers for generating two steerable ultrasound beams. An aiming device is provided for electronically steering and focusing the two ultrasound beams so that they cross each other confocally at the target. Further embodiments employ pluralities of transducers, arrays, or both.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGYCAMBRIDGE MA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lele, Padmakar P Westford, MA 6 1129
Rolt, Kenneth D Medford, MA 15 398

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