Method and apparatus for anchorage and suspension cell culture
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United States of America Patent
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Mar 26, 1996
Issued Date -
N/A
app pub date -
Nov 30, 1994
filing date -
Jan 29, 1993
priority date (Note) -
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Abstract
A method and apparatus cultivates anchorage and nonanchorage cell in a reactor. A reactor includes a basket type packed bed and an internal recirculation device. The basket includes a top and bottom portion for allowing medium to flow uniformly through the basket. Medium flows downwardly from the top of the basket through the basket for providing gentle flow and preventing removal of cells from the carrier. Preferably, the carrier is formed of a fiber matrix.
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