Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase

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United States of America Patent

PATENT NO 5503978
SERIAL NO

08238863

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods are described for the identification and preparation of DNA ligands to the HIV-1 reverse transcriptase protein. The invention encompasses specific ssDNA ligands to HIV-1 reverse transcriptase identified by the SELEX method including ssDNA ligands that inhibit the activity of HIV-1 reverse transcriptase.

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Patent Owner(s)

Patent OwnerAddress
GILEAD SCIENCES INC333 LAKESIDE DRIVE FOSTER CITY CA 94404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Feigon, Juli Los Angeles, CA 2 241
Gold, Larry Boulder, CO 241 11989
Schneider, Daniel J Boulder, CO 44 1399

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