Aminoglycoside formulation for aerosolization
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United States of America Patent
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Apr 16, 1996
Grant Date -
N/A
app pub date -
Oct 19, 1994
filing date -
Oct 19, 1994
priority date (Note) -
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Abstract
An aminoglycoside formulation for delivery by aerosolization. The concentrated aminoglycoside formulation containing an efficacious amount of aminoglycoside able to inhibit 95-100% of susceptible bacteria. Aminoglycoside formulated in 5 ml solution of a quarter normal saline having pH between 5.5 and 6.5. The method for treatment of endobronchial infections by a produced by a formulation delivered as an aerosol having mass medium average diameter predominantly between 1 to 5 .mu., produced by a jet or ultrasonic nebulizer.
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