Fixed tissue medical devices comprising albumin-binding dyes
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United States of America Patent
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Apr 23, 1996
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N/A
app pub date -
Apr 8, 1993
filing date -
Apr 8, 1993
priority date (Note) -
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Abstract
An implantable medical device is provided which comprises a fixed tissue incorporating an amount of an albumin-binding dye effective to form a coating of endogenous albumin on said device when the device is in contact with a physiological fluid containing albumin. These albumin-binding dyes have been found to significantly reduce calcification when incorporated in tissue heart valves. A method of increasing the albumin-binding ability of an implantable medical device is also provided.
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