Process for preparing therapeutic compositions containing nanoparticles
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United States of America Patent
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Apr 23, 1996
Grant Date -
N/A
app pub date -
Feb 14, 1995
filing date -
Feb 14, 1995
priority date (Note) -
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Abstract
A process of preparing nanoparticulate drug substances comprising the steps of: preparing a premix of the drug substance and a surface modifier, and subjecting the premix to mechanical means to reduce the particle size of the drug substance, the mechanical means producing shear, impact, cavitation and attrition.
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