Capillary electrophoresis method and apparatus for electric field uniformity and minimal dispersion of sample fractions
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United States of America Patent
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Apr 30, 1996
Grant Date -
N/A
app pub date -
Feb 28, 1995
filing date -
Feb 28, 1995
priority date (Note) -
Expired
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Abstract
A capillary electrophoresis method and apparatus for reducing dispersion of sample fractions are disclosed. The capillary tube in which the electrophoresis is performed has been flared, at least at its sample entrance end, to remove sharp corners which contribute to aberrations in the electric field distribution in a radial direction and result in differential migration of molecules depending on their proximity to the sharp corners. The flared tube, in contrast to a conventional tube, provides a more uniform electric field for electrophoresis and reduces undesired dispersion of the samples.
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