Biodegradable hydrogel copolymer as drug delivery matrix
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United States of America Patent
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May 7, 1996
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N/A
app pub date -
Jun 30, 1994
filing date -
May 17, 1994
priority date (Note) -
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Abstract
This invention concerns the thermoplastic, biodegradable hydrogel copolymer which is easily degraded and excreted in human body by the hydrolysis of intramolecular ester and amide bond. The structure of present copolymer comprises i) hydrophilic and swellable soft domain consisting of polyethyleneoxide (PEO), and ii) hydrophobic, biodegradable, crystallizable and non-swellable hard domain consisting of polylactide (PLA), polyglycolide (PGA), polylactideglycolide (PLGA) and polycaprolactone (PCL).
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