Peptidyl ketoamides
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United States of America Patent
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May 7, 1996
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app pub date -
Jun 24, 1993
filing date -
Sep 21, 1992
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Abstract
A novel class of peptide .alpha.-ketoamides useful for selectively inhibiting serine proteases, selectively inhibiting cysteine proteases, generally inhibiting all serine proteases, and generally inhibiting all cysteine proteases, having the formula Y--CO--AA.sup.2 --AA.sup.1 --CO--NH--X. Processes for the synthesis of peptidyl .alpha.-ketoamide derivatives.
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