Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage

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United States of America Patent

PATENT NO 5516637
SERIAL NO

08258026

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Abstract

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The present invention relates to a fusion protein, comprising a pilin protein or a portion thereof and a heterologous polypeptide (target protein). In a preferred embodiment it relates to a method for displaying the target protein on the outer surface of a bacterial host cell capable of forming pilus. In certain embodiments, it is desirable that the pilus is a receptor for bacteriophage attachment and infection. The F pilus is preferred.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DADE BEHRING INC.DEERFIELD, IL1

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huang, Grace P Miami, FL 1 205
Rhode, Peter R Miami, FL 10 328
Stinson, Jeffrey R Davie, FL 24 427
Wong, Hing C Ft. Lauderdale, FL 71 628

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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