Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
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United States of America Patent
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May 14, 1996
Issued Date -
N/A
app pub date -
Mar 1, 1995
filing date -
Oct 30, 1991
priority date (Note) -
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Abstract
This invention relates to a composition comprising a tramadol material and a nonsteroidal antiinflammatory drug, and its use. The compositions are pharmacologically useful in treating pain and tussive conditions. The compositions are also subject to less opioid side-effects such as abuse liability, tolerance, constipation and respiratory depression. Furthermore, where the components of the compositions are within certain ratios the pharmacological effects of the compositions are superadditive (synergistic).
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