Pyrrolidine-containing monomers and oligomers
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United States of America Patent
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May 21, 1996
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app pub date -
Jan 11, 1994
filing date -
Jan 11, 1994
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Abstract
Novel pyrrolidine monomers bearing various functional groups are used to prepare oligomeric structures. The pyrrolidine monomers can be joined via standard phosphate linkages including phosphodiester and phosphorothioate linkages. Useful functional groups include nucleobases as well as polar groups, hydrophobic groups, ionic groups, aromatic groups and/or groups that participate in hydrogen-bonding.
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