Benzamide derivatives and pharmaceutical composition comprising the same
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United States of America Patent
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May 28, 1996
Grant Date -
N/A
app pub date -
Mar 31, 1994
filing date -
Apr 13, 1993
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Compounds having the structure below ##STR1## and pharmaceutically acceptable salts thereof exhibit vasopressin antagonistic activity, vasodilating activity, hypotensive activity, activity for inhibiting saccharide release in the liver, activity for inhibiting growth of mesagium cells, water diuretic activity, platelet agglutination inhibitory activity, oxytocin antagonistic activity and the like, and are useful in treating or preventing hypertension, heart failure, renal insufficiency, edema, ascites, vasopressin parasecretion syndrome, hepatocirrhosis, hyponatremia, hypokalemia, diabetic or circulation disorder, oxytocin related diseases and the like.
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