Non-invasive method of determining inflammation of the gastrointestinal tract
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United States of America Patent
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Jun 11, 1996
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N/A
app pub date -
Sep 20, 1994
filing date -
Sep 20, 1994
priority date (Note) -
Expired
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Abstract
A non-invasive method of determining the presence of inflammation in a region of the gastrointestinal tract of an organism comprises introducing an arterial dilating agent into the circulatory system that provides blood flow to that region, then introducing a blood flow marking medium into the circulation providing blood flow to that region. The amount of blood flow marking medium present in that region is then monitored as an indication of the extent of inflammation present in that region. The capability of inflamed gastrointestinal tract tissue to take up increased amounts of the blood flow marking medium provides an indication of the presence of an abnormal pathologic process in that region of the gastrointestinal tract. In the preferred embodiment of the method, the arterial dilator is dipyridamole. The blood flow marking medium is thallium-201, and its accumulation in the region of the gastrointestinal tract is monitored by measuring the radioactive emissions by thallium-201 scintigraphy. The method permits the non-invasive determination of the presence of inflammation in the gastrointestinal tract of an organism.
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