Detection and therapy of lesions with biotin/avidin conjugates
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United States of America Patent
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Jun 11, 1996
Grant Date -
N/A
app pub date -
Aug 21, 1992
filing date -
Aug 21, 1992
priority date (Note) -
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Abstract
Methods are provided for detecting and/or treating lesions in a patient. The methods use a targeting composition comprised of a biotin and targeting protein conjugate or an avidin and targeting protein conjugate; optionally, a clearing composition comprised of avidin, when the targeting composition is a biotin conjugate, or biotin, when the targeting composition is a avidin conjugate; a detection or therapeutic composition comprised of a conjugate of avidin or biotin with a targeting protein and detection or therapeutic agent; and, optionally, another detection or therapeutic composition comprised of avidin or biotin conjugated to a detection or therapeutic agent. Compositions and kits useful in the methods are also provided.
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