Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same

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United States of America Patent

PATENT NO 5525357
SERIAL NO

08121169

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Abstract

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A polymeric composition capable of releasing nitric oxide including a polymer and a nitric oxide-releasing N.sub.2 O.sub.2.sup.- functional group bound to the polymer; pharmaceutical compositions including the polymeric composition; and methods for treating biological disorders in which dosage with nitric oxide is beneficial. The compositions can be used as and/or incorporated into implants, injectables, condoms, prosthesis coatings, patches, and the like for use in a wide variety of medical applications.

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Patent Owner(s)

Patent OwnerAddress
HEALTH AND HUMAN SERIVCES UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OFOFFICE OF TECHNOLOGY TRANSFER NATIONAL INSTITUTES OF HEALTH BOX OTT BETHESDA MD 20892-9902

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hrabie, Joseph A Frederick, MD 27 1443
Keefer, Larry K Bethesda, MD 54 3016
Saavedra, Joseph E Thurmont, MD 18 812

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