Pteridine nucleotide analogs as fluorescent DNA probes

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United States of America Patent

PATENT NO 5525711
SERIAL NO

08245923

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Abstract

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The invention provides novel pteridine nucleotides which are highly fluorescent under physiological conditions and which may be used in the chemical synthesis of fluorescent oligonucleotidcs. The invention further provides for fluorescent oligonucleotides comprising one or more pteridine nucleotides. In addition the invention provides for pteridine nucleotide triphosphates which may be used as the constituent monomers in DNA amplification procedures.

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Patent Owner(s)

Patent OwnerAddress
UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICESNATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY TRANSFER 6011 EXECUTIVE BLVD STE 325 ROCKVILLE MD 20852 ROCKVILLE MD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balis, Frank Bethesda, MD 3 503
Davis, Michael D Rockville, MD 18 683
Hawkins, Mary E Potomac, MD 3 503
Pfleiderer, Wolfgang Konstanz, DE 33 2186

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