Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding
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United States of America Patent
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Jun 18, 1996
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app pub date -
Jun 30, 1994
filing date -
Apr 9, 1992
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Abstract
This invention relates to chelating agents useful for coupling metal ions to biologically active molecules. In particular, isothiocyanate derived thiocarbonyls for chelating metals such as technetium are provided that can be conjugated to a targeting molecule such as an antibody, a peptide or a protein.
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