Implantable capsule for enhancing cell electric signals
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United States of America Patent
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Jun 25, 1996
Grant Date -
N/A
app pub date -
Jun 27, 1994
filing date -
Jun 27, 1994
priority date (Note) -
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status (Latency Note)
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Abstract
A capsule for encapsulating implantable cells for improving the detectability of electrical signals generated by the cells is provided. The capsule includes a low-conductivity (high electrical resistance) membrane and a semi-permeable (low electrical resistance) membrane. The low-conductivity membrane seals around the circumference of the cell mass between the electrical poles of the capsule, and further extends for increasing the electrical resistance between the poles. The semi-permeable membrane enables nutrients and waste materials to flow to and from the cell mass. The semi-permeable membrane encloses at least one of the poles of the cell mass, and cooperates with the low-conductivity membrane to completely enclose the cell mass. The low-conductivity membrane may enclose one of the poles, if desired. Electrodes are used to detect the electrical signals from the cell mass. Various methods of making the capsule are disclosed.
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