Sterilized cyanoacrylate adhesive composition, and a method of making such a composition
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United States of America Patent
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Jun 25, 1996
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N/A
app pub date -
Dec 21, 1994
filing date -
Dec 23, 1993
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Abstract
A curable cyanoacrylate adhesive composition intended for medical and/or veterinary uses is sterilized in liquid form by gamma irradiation. The composition comprises a) a cyanoacrylate monomer b) a combination of an anionic stabilizer and a free-radical stabilizer in amounts effective to stabilize the composition during irradiation and to stabilize the sterilized composition during storage prior to cure, wherein the free radical stabilizer is a selected phenolic antioxidant (but not including hydroquinone). The preferred free radical stabilizer is butylated hydroxyanisole. After irradiation the cyanoacrylate monomer is substantially ungelled.
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