US Patent No: 5,534,028

Number of patents in Portfolio can not be more than 2000

Hydrogel intervertebral disc nucleus with diminished lateral bulging

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Abstract

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A prosthetic nucleus for a vertebral disc is made of a hydrogel material. The hydrogel prosthetic nucleus has a shape generally conforming to the natural nucleus pulposus, and it exhibits diminished lateral bulging under high compressive loads. The hydrogel has a water content of from 30% to 90% and has a compressive strength of 4 MNm.sup.-2 or greater. When the hydrogel material is dehydrated, it has a dimension of less than half of that of the hydrated hydrogel nucleus. The prosthetic nucleus may be formed of two or more pieces of hydrogel material which pieces, when combined, have a shape generally conforming to the natural nucleus. The prosthetic nucleus may have a stiff posterior periphery and/or a thickened anterior wall.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
HOWMEDICA OSTEONICS CORP.MAHWAH, NJ484
PFIZER INC.NEW YORK, NY677

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bao, Qi-Bin New York, NY 41 4427
Higham, Paul A New York, NY 15 3011

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (3)
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* 4,309,777 Artificial intervertebral disc 722 1980
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RAY MEDICA, INC. (2)
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ZIMMER GMBH (1)
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HOWMEDICA OSTEONICS CORP. (1)
* 5,047,055 Hydrogel intervertebral disc nucleus 694 1990
 
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (1)
* 4,911,718 Functional and biocompatible intervertebral disc spacer 546 1988
 
WARSAW ORTHOPEDIC, INC. (1)
* 2002/0138,146 Anterior expandable spinal fusion cage system 27 2002
 
PFIZER HOSPITAL PRODUCTS GROUP, INC. (1)
* 4,714,469 Spinal implant 588 1987
* Cited By Examiner

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (22)
* 2003/0026,788 Use of extracellular matrix tissue to preserve cultured cell phenotype 17 2002
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* 2007/0106,387 ASSOCIATING HYDROGELS FOR NUCLEUS PULPOSUS REPLACEMENT IN INTERVERTEBRAL DISCS 10 2006
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8,834,526 Methods and apparatus for treating spinal stenosis 0 2007
* 2010/0320,639 Medical Implants with Pre-Settled Cores and Related Methods 2 2008
8,157,865 Apparatus and method for stabilizing adjacent bone portions 2 2010
* 2010/0185,292 APPARATUS AND METHOD FOR STABILIZING ADJACENT BONE PORTIONS 9 2010
8,834,496 Soft tissue repair methods and apparatus 0 2011
8,764,835 Intervertebral disc treatment methods and apparatus 0 2011
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SEMINIS VEGETABLE SEEDS, INC. (1)
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Spinal Kinetics Inc. (1)
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AEOLIN, LLC (1)
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RESSPOND SPINAL SYSTEMS (1)
8,795,375 Modular nucleus pulposus prosthesis 0 2009
 
Flexuspine, Inc. (33)
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8,123,810 Expandable intervertebral implant with wedged expansion member 30 2005
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7,708,778 Expandable articulating intervertebral implant with cam 38 2005
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8,603,168 Artificial functional spinal unit system and method for use 4 2006
8,118,869 Dynamic interbody device 16 2006
8,052,723 Dynamic posterior stabilization systems and methods of use 21 2006
7,799,082 Artificial functional spinal unit system and method for use 29 2006
7,794,480 Artificial functional spinal unit system and method for use 43 2006
7,785,351 Artificial functional spinal implant unit system and method for use 53 2006
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9,066,811 Artificial functional spinal unit system and method for use 0 2007
8,940,022 Artificial functional spinal unit system and method for use 1 2007
8,597,358 Dynamic interbody devices 7 2007
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7,959,677 Artificial functional spinal unit system and method for use 22 2007
8,523,912 Posterior stabilization systems with shared, dual dampener systems 4 2007
8,267,965 Spinal stabilization systems with dynamic interbody devices 9 2007
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8,940,051 Interbody device insertion systems and methods 1 2013
 
KYPHON SARL (90)
* 6,500,178 Spine distraction implant and method 286 1999
6,379,355 Spine distraction implant and method 175 1999
6,332,882 Spine distraction implant 164 1999
7,621,950 Expandable intervertebral spacer 102 2000
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6,796,983 Spine distraction implant and method 196 2001
7,101,375 Spine distraction implant 205 2001
6,902,566 Spinal implants, insertion instruments, and methods of use 132 2001
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6,514,256 Spine distraction implant and method 291 2001
6,478,796 Spin distraction implant and method 231 2001
6,582,433 Spine fixation device and method 358 2001
7,201,751 Supplemental spine fixation device 244 2001
6,699,246 Spine distraction implant 292 2001
6,699,247 Spine distraction implant 194 2001
6,926,728 Curved dilator and method 182 2001
6,652,534 Apparatus and method for determining implant size 157 2001
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6,712,819 Mating insertion instruments for spinal implants and methods of use 257 2001
6,652,527 Supplemental spine fixation device and method 220 2001
6,695,842 Interspinous process distraction system and method with positionable wing and method 313 2001
7,189,234 Interspinous process implant sizer and distractor with a split head and size indicator and method 76 2001
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7,029,473 Deflectable spacer for use as an interspinous process implant and method 67 2002
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7,833,246 Interspinous process and sacrum implant and method 2 2003
7,497,859 Tools for implanting an artificial vertebral disk 30 2003
7,306,628 Interspinous process apparatus and method with a selectably expandable spacer 171 2003
7,273,496 Artificial vertebral disk replacement implant with crossbar spacer and method 72 2003
7,083,649 Artificial vertebral disk replacement implant with translating pivot point 139 2003
6,966,929 Artificial vertebral disk replacement implant with a spacer 124 2003
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7,217,291 System and method for replacing degenerated spinal disks 149 2003
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7,335,203 System and method for immobilizing adjacent spinous processes 173 2004
7,901,432 Method for lateral implantation of spinous process spacer 11 2004
7,758,619 Spinous process implant with tethers 31 2004
7,549,999 Interspinous process distraction implant and method of implantation 19 2004
7,510,567 Spinal implants, insertion instruments, and methods of use 25 2004
7,695,513 Distractible interspinous process implant and method of implantation 27 2004
7,452,379 Artificial vertebral disk replacement implant with crossbar spacer and method 2 2004
7,481,840 Multi-piece artificial spinal disk replacement device with selectably positioning articulating element 53 2004
7,691,146 Method of laterally inserting an artificial vertebral disk replacement implant with curved spacer 31 2004
7,670,377 Laterally insertable artifical vertebral disk replacement implant with curved spacer 29 2004
7,520,899 Laterally insertable artificial vertebral disk replacement implant with crossbar spacer 34 2004
7,503,935 Method of laterally inserting an artificial vertebral disk replacement with translating pivot point 51 2004
7,320,707 Method of laterally inserting an artificial vertebral disk replacement implant with crossbar spacer 77 2004
7,481,839 Bioresorbable interspinous process implant for use with intervertebral disk remediation or replacement implants and procedures 27 2004
7,575,600 Artificial vertebral disk replacement implant with translating articulation contact surface and method 52 2004
7,524,324 System and method for an interspinous process implant as a supplement to a spine stabilization implant 64 2004
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7,601,170 Inter-cervical facet implant and method 67 2005
7,591,851 Inter-cervical facet implant and method 69 2005
7,955,356 Laterally insertable interspinous process implant 8 2005
7,918,877 Lateral insertion method for spinous process spacer with deployable member 8 2005
7,621,939 Supplemental spine fixation device and method 26 2005
8,100,944 Inter-cervical facet implant and method for preserving the tissues surrounding the facet joint 19 2005
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7,909,853 Interspinous process implant including a binder and method of implantation 14 2005
8,048,117 Interspinous process implant and method of implantation 10 2005
8,172,877 Inter-cervical facet implant with surface enhancements 20 2005
8,128,660 Inter-cervical facet joint implant with locking screw system 20 2005
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* 2006/0241,597 Inter-cervical facet joint implant with locking screw system 66 2005
8,070,778 Interspinous process implant with slide-in distraction piece and method of implantation 7 2006
7,931,674 Interspinous process implant having deployable wing and method of implantation 24 2006
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7,828,822 Spinous process implant 24 2006
8,029,540 Inter-cervical facet implant with implantation tool 15 2006
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8,118,838 Inter-cervical facet implant with multiple direction articulation joint and method for implanting 19 2006
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7,476,251 Interspinous process apparatus and method with a selectably expandable spacer 64 2006
7,803,190 Interspinous process apparatus and method with a selectably expandable spacer 18 2006
8,012,209 Interspinous process implant including a binder, binder aligner and method of implantation 7 2007
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PIONEER SURGICAL TECHNOLOGY, INC. (7)
7,001,433 Artificial intervertebral disc device 51 2002
* 2003/0220,691 Artificial intervertebral disc device 25 2002
8,241,360 Artificial disc device 7 2004
8,262,731 Artificial disc device 2 2005
* 2008/0109,081 Joint Arthroplasty Devices Having Articulating Members 12 2007
9,241,807 Systems and methods for inserting a spinal device 0 2012
9,233,011 Systems and apparatuses for inserting an implant in intervertebral space 0 2014
 
HOWMEDICA OSTEONICS CORP. (9)
* 5,976,186 Hydrogel intervertebral disc nucleus 496 1996
6,280,475 Hydrogel intervertebral disc nucleus implantation method 176 1999
6,783,721 Method of making an ion treated hydrogel 13 2001
* 7,282,165 Wear resistant hydrogel for bearing applications 16 2004
* 2005/0236,742 Wear resistant hydrogel for bearing applications 2 2004
7,332,117 Ion treated hydrogel 8 2004
* 2004/0212,130 Ion treated hydrogel 0 2004
8,197,547 Radiovisible hydrogel intervertebral disc nucleus 0 2005
* 2006/0255,503 Radiovisible hydrogel intervertebral disc nucleus 2 2006
 
OSTEOTECH, INC. (2)
6,530,955 Ramp-shaped intervertebral implant 114 2001
6,383,221 Method for forming an intervertebral implant 133 2001
 
Intrinsic Therapeutics, Inc. (37)
6,482,235 Devices and methods of vertebral disc augmentation 271 2000
7,220,281 Implant for reinforcing and annulus fibrosis 92 2002
7,094,258 Methods of reinforcing an annulus fibrosis 54 2002
6,883,520 Methods and apparatus for dynamically stable spinal implant 164 2002
7,124,761 Deployment devices and methods for vertebral disc augmentation 62 2002
* 2003/0093,155 Deployment devices and methods for vertebral disc augmentation 7 2002
7,717,961 Apparatus delivery in an intervertebral disc 25 2003
7,507,243 Devices and method for augmenting a vertebral disc 32 2003
7,563,282 Method of supporting nucleus pulposus 27 2003
* 2004/0034,429 Anchored anulus method 22 2003
7,727,241 Device for delivering an implant through an annular defect in an intervertebral disc 31 2004
8,002,836 Method for the treatment of the intervertebral disc anulus 3 2004
7,749,275 Method of reducing spinal implant migration 22 2004
7,513,911 Method of implanting dynamically stable spinal implant 51 2004
7,553,329 Stabilized intervertebral disc barrier 61 2004
7,658,765 Resilient intervertebral disc implant 22 2004
8,231,678 Method of treating a herniated disc 8 2006
7,879,097 Method of performing a procedure within a disc 26 2006
* 7,524,333 Method of anchoring an implant in an intervertebral disc 51 2006
7,500,978 Method for delivering and positioning implants in the intervertebral disc environment 24 2006
7,553,330 Methods of reinforcing an intervertebral disc annulus 36 2006
7,998,213 Intervertebral disc herniation repair 11 2006
7,972,337 Devices and methods for bone anchoring 23 2006
7,959,679 Intervertebral anulus and nucleus augmentation 13 2007
7,867,278 Intervertebral disc anulus implant 20 2008
8,025,698 Method of rehabilitating an anulus fibrosus 11 2009
8,021,425 Versatile method of repairing an intervertebral disc 12 2009
8,454,612 Method for vertebral endplate reconstruction 3 2009
8,114,082 Anchoring system for disc repair 21 2009
8,323,341 Impaction grafting for vertebral fusion 4 2009
8,361,155 Soft tissue impaction methods 3 2010
8,409,284 Methods of repairing herniated segments in the disc 4 2011
8,257,437 Methods of intervertebral disc augmentation 7 2011
8,394,146 Vertebral anchoring methods 3 2011
9,226,832 Interbody fusion material retention methods 0 2013
9,039,741 Bone anchor systems 2 2013
9,333,087 Herniated disc repair 0 2014
 
NAXCOR (1)
6,342,074 Anterior lumbar interbody fusion implant and method for fusing adjacent vertebrae 180 2000
 
GMEDELAWARE 2 LLC (54)
8,163,017 Facet arthroplasty devices and methods 0 2003
8,092,532 Facet arthroplasty devices and methods 0 2003
8,070,811 Facet arthroplasty devices and methods 0 2003
8,066,771 Facet arthroplasty devices and methods 0 2003
8,187,303 Anti-rotation fixation element for spinal prostheses 0 2004
7,051,451 Facet joint prosthesis measurement and implant tools 161 2004
8,419,770 Spinal facet implants with mating articulating bearing surface and methods of use 0 2004
7,691,145 Prostheses, systems and methods for replacement of natural facet joints with artificial facet joint surfaces 23 2004
7,608,104 Prostheses, tools and methods for replacement of natural facet joints with artifical facet joint surfaces 20 2004
7,588,578 Surgical measurement systems and methods 11 2004
7,507,242 Surgical measurement and resection framework 15 2004
7,993,373 Polyaxial orthopedic fastening apparatus 15 2005
7,674,293 Crossbar spinal prosthesis having a modular design and related implantation methods 38 2005
7,722,647 Apparatus and method for posterior vertebral stabilization 10 2005
7,566,345 Prosthesis for the replacement of a posterior element of a vertebra 25 2005
7,445,635 Method and apparatus for spine joint replacement 59 2005
8,398,681 Adjacent level facet arthroplasty devices, spine stabilization systems, and methods 2 2005
8,313,511 Facet joint replacement 0 2005
7,618,453 Facet joint replacement 22 2005
7,406,775 Implantable orthopedic device component selection instrument and methods 63 2005
8,066,740 Facet joint prostheses 0 2005
8,221,461 Crossbar spinal prosthesis having a modular design and systems for treating spinal pathologies 0 2005
8,062,336 Polyaxial orthopedic fastening apparatus with independent locking modes 13 2005
8,523,907 Prostheses, tools and methods for replacement of natural facet joints with artificial facet joint surfaces 0 2006
7,608,106 Facet arthroplasty devices and methods 9 2006
8,764,801 Facet joint implant crosslinking apparatus and method 0 2006
7,290,347 Facet joint prosthesis measurement and implant tools 49 2006
8,231,655 Prostheses and methods for replacement of natural facet joints with artificial facet joint surfaces 6 2006
8,562,649 System and method for multiple level facet joint arthroplasty and fusion 0 2006
7,914,556 Arthroplasty revision system and method 2 2006
8,579,941 Linked bilateral spinal facet implants and methods of use 0 2007
7,621,955 Facet joint replacement 23 2007
8,496,686 Minimally invasive spine restoration systems, devices, methods and kits 0 2007
8,702,755 Angled washer polyaxial connection for dynamic spine prosthesis 1 2007
8,491,635 Crossbar spinal prosthesis having a modular design and related implantation methods 0 2007
8,425,557 Crossbar spinal prosthesis having a modular design and related implantation methods 4 2007
8,496,687 Crossbar spinal prosthesis having a modular design and related implantation methods 1 2007
8,900,273 Taper-locking fixation system 0 2008
9,198,766 Prostheses, tools, and methods for replacement of natural facet joints with artificial facet joint surfaces 0 2008
9,056,016 Polyaxial adjustment of facet joint prostheses 0 2008
8,353,933 Facet joint replacement 0 2008
8,409,254 Prostheses, tools and methods for replacement of natural facet joints with artificial facet joint surfaces 0 2008
8,675,930 Implantable orthopedic device component selection instrument and methods 0 2008
9,050,144 System and method for implant anchorage with anti-rotation features 0 2008
8,702,759 System and method for bone anchorage 0 2008
8,308,768 System and method for facet joint replacement 0 2008
8,252,027 System and method for facet joint replacement 1 2008
8,211,147 System and method for facet joint replacement 0 2008
8,206,418 System and method for facet joint replacement with detachable coupler 8 2008
8,906,063 Spinal facet joint implant 0 2008
8,777,994 System and method for multiple level facet joint arthroplasty and fusion 0 2008
7,998,177 Linked bilateral spinal facet implants and methods of use 12 2008
7,998,178 Linked bilateral spinal facet implants and methods of use 12 2008
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NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (1)
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OSTEOBIOLOGICS (1)
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QUANDARY MEDICAL, LLC (2)
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Bridport-Gundry PLC c/o Pearsalls Implants (1)
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7,776,352 Systems and methods for controlling and forming polymer hydrogels 1 2006
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Loop Telecommunication International, Inc. (1)
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SPINAL CONCEPTS, INC. (1)
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MEDGEM, LLC (4)
9,005,290 Spinal interbody device 0 2008
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9,144,502 Spinal interbody device 0 2015
 
FLEXUSPINE (2)
7,753,958 Expandable intervertebral implant 79 2005
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NUVASIVE, INC. (14)
* 2008/0269,900 Surgical Implants 2 2005
* 2008/0228,273 Implants 2 2006
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8,167,915 Methods and apparatus for treating spinal stenosis 9 2006
* 2008/0015,697 Prosthetic spinal disc and related methods 12 2007
* 2009/0018,658 Methods and apparatus for treating spinal stenosis 17 2007
7,946,236 Using zigzags to create three-dimensional embroidered structures 16 2007
7,942,104 3-dimensional embroidery structures via tension shaping 2 2007
* 2008/0173,223 3-DIMENSIONAL EMBROIDERY STRUCTURES VIA TENSION SHAPING 3 2007
8,282,681 Bioresorbable spinal implant and related methods 0 2008
* 2009/0048,677 Bioresorbable Spinal Implant and Related Methods 28 2008
8,377,135 Textile-based surgical implant and related methods 0 2009
* 2011/0098,746 Methods and Apparatus For Treating Spinal Stenosis 2 2011
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REPLICATION MEDICAL, INC. (10)
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* 2003/0055,506 Hydrogel-based prosthetic device for replaceing at least a part of the nucleus of a spinal disc 1 2001
* RE42837 Spinal nucleus implant 3 2003
7,204,897 Hydrogel-based prosthetic device for replacing at least a part of the nucleus of a spinal disc 10 2004
* 2005/0171,611 Hydrogel-based prosthetic device for replacing at least a part of the nucleus of a spinal disc 3 2004
7,806,934 Radially compressed dehydrated spinal nucleus implants 1 2005
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* 2010/0222,881 VESSEL PROTECTION DEVICE 0 2009
 
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6,547,823 Intervertebral implant 118 1999
6,277,149 Ramp-shaped intervertebral implant 311 1999
7,147,665 Threaded cylindrical multidiscoid single or multiple array disc prosthesis 102 1999
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6,402,785 Artificial disc implant 311 2000
6,620,196 Intervertebral disc nucleus implants and methods 211 2000
6,733,531 Anchoring devices and implants for intervertebral disc augmentation 222 2000
* 6,613,089 Laterally expanding intervertebral fusion device 44 2000
RE42576 Human spinal disc prosthesis 0 2001
6,949,105 Method and apparatus for stereotactic implantation 42 2001
7,641,692 Implantable joint prosthesis 14 2001
* 2002/0128,715 Implantable joint prosthesis 145 2001
6,562,045 Machining apparatus 26 2001
6,706,067 Spinal intervertebral implant and method of making 91 2001
* 2003/0040,800 Apparatus and method for replacing the nucleus pulposus of an intervertebral disc or for replacing an entire intervertebral disc 30 2001
6,733,505 Apparatus and method for loading a prosthetic nucleus into a deployment cannula to replace the nucleus pulposus of an intervertebral disc 21 2001
RE42480 Human spinal disc prothesis with hinges 4 2001
7,503,933 Lordotic interbody spinal fusion implants 95 2002
* 2003/0040,798 Lordotic interbody spinal fusion implants 33 2002
7,025,787 Implantable joint prosthesis and associated instrumentation 131 2002
7,081,120 Instrumentation and method for delivering an implant into a vertebral space 165 2002
* 2003/0125,748 Instrumentation and method for delivering an implant into a vertebral space 48 2002
* 6,911,045 Bio-implant insertion instrument 24 2003
* 2003/0225,414 Bio-implant insertion instrument 1 2003
6,974,479 System and method for blocking and/or retaining a prosthetic spinal implant 118 2003
* 2004/0210,310 Implant system and method for intervertebral disc augmentation 66 2003
* 2004/0111,161 System and method for blocking and/or retaining a prosthetic spinal implant 30 2003
7,601,174 Wear-resistant endoprosthetic devices 18 2003
7,828,845 Laterally expanding intervertebral fusion device 27 2003
7,662,185 Intervertebral implants 16 2003
7,204,851 Method and apparatus for delivering an intervertebral disc implant 69 2003
* 2004/0117,019 Method and apparatus for delivering an intervertebral disc implant 49 2003
7,179,262 Method and apparatus for stereotactic implantation 6 2003
* 2005/0059,976 Method and apparatus for stereotactic implantation 5 2003
* 2005/0277,921 Prosthetic joint and nucleus supplement 24 2004
* 7,789,914 Implant having arcuate upper and lower bearing surfaces along a longitudinal axis 29 2004
7,618,461 Composite intervertebral disc implants and methods for forming the same 23 2004
* 7,503,936 Methods for forming and retaining intervertebral disc implants 40 2004
7,726,002 Processes for making spinal intervertebral implant, interconnections for such implant 7 2004
8,728,160 Expandable intervertebral spacer 1 2005
8,333,985 Non-glycerol stabilized bone graft 0 2005
7,780,708 Implant retaining device 10 2005
7,776,090 Inter-cervical facet implant and method 81 2005
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* 2006/0217,806 Spinal system and method including lateral approach 20 2005
7,763,050 Inter-cervical facet implant with locking screw and method 47 2005
7,520,900 Intervertebral disc nucleus implants and methods 19 2005
8,066,749 Implant for stabilizing a bone graft during spinal fusion 17 2005
* 2007/0225,806 Arthroplasty device 20 2006
8,480,744 Method of preparing an implant for delivery into a vertebral space 1 2006
8,066,750 Port structures for non-rigid bone plates 0 2006
7,857,818 Method and apparatus for delivering an intervertebral disc implant 5 2007
* 2007/0198,025 METHOD AND APPARATUS FOR DELIVERING AN INTERVERTEBRAL DISC IMPLANT 37 2007
7,837,734 System and method for replacing degenerated spinal disks 84 2007
* 7,776,095 Spinal system and method including lateral approach 37 2007
8,092,541 Method of using an anti-growth matrix as a barrier for cell attachment and osteo-inductive factors 3 2007
* 2009/0036,988 METHOD OF USING AN ANTI-GROWTH MATRIX AS A BARRIER FOR CELL ATTACHMENT AND OSTEO-INDUCTIVE FACTORS 2 2007
8,372,157 Joint revision implant 2 2008
* 2009/0143,862 SYSTEM AND METHOD FOR BLOCKING AND/OR RETAINING A PROSTHETIC SPINAL IMPLANT 54 2009
8,092,542 Implantable joint prosthesis 5 2009
7,988,734 Spinal system and method including lateral approach 8 2010
8,672,980 Implant retaining device 0 2010
8,021,430 Anatomic spinal implant having anatomic bearing surfaces 67 2010
8,425,530 Apparatus for sizing a facet joint 5 2011
8,444,696 Anatomic spinal implant having anatomic bearing surfaces 3 2011
9,034,042 Method of using an anti-growth matrix as a barrier for cell attachment and osteo-inductive factors 0 2011
8,858,638 Spinal implant 0 2013
 
X-spine Systems, Inc. (1)
8,216,316 Prosthetic implant with biplanar angulation and compound angles 7 2008
 
SPINAL ELEMENTS, INC. (18)
7,846,183 Vertebral facet joint prosthesis and method of fixation 88 2004
* 2005/0177,240 Vertebral facet joint prosthesis and method of fixation 139 2004
8,652,137 Vertebral facet joint drill and method of use 13 2008
7,998,172 Vertebral facet joint prosthesis and method of fixation 46 2009
* 2009/0204,152 VERTEBRAL FACET JOINT PROSTHESIS AND METHOD OF FIXATION 29 2009
8,992,533 Vertebral facet joint drill and method of use 4 2010
8,858,597 Vertebral facet joint prosthesis and method of fixation 7 2010
8,740,949 Methods and apparatus for stabilizing bone 10 2011
9,301,786 Methods and apparatus for stabilizing bone 0 2011
8,998,953 Vertebral facet joint prosthesis and method of fixation 3 2011
D724733 Interbody bone implant 5 2011
9,271,765 Vertebral facet joint fusion implant and method for fusion 0 2012
9,060,787 Method of using a vertebral facet joint drill 1 2012
8,740,942 Vertebral facet joint prosthesis and method of fixation 10 2013
8,882,804 Vertebral facet joint prosthesis and method of fixation 6 2013
9,179,943 Methods and apparatus for stabilizing bone 0 2014
D748793 Interbody bone implant 0 2015
D748262 Interbody bone implant 0 2015
 
SYNTHES USA, LLC (2)
8,287,595 Hydrogel balloon prosthesis for nucleus pulposus 1 2006
* 2007/0073,402 Hydrogel balloon prosthesis for nucleus pulposus 39 2006
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (3)
7,156,877 Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs 51 2002
7,641,691 Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs 5 2006
* 2009/0234,457 SYSTEMS, DEVICES AND METHODS FOR TREATMENT OF INTERVERTEBRAL DISORDERS 23 2009
 
K2M, INC. (10)
8,864,831 Fixation of elastomer to rigid structures 0 2006
7,776,092 Elastomeric intervertebral disc prosthesis 7 2006
* 2008/0306,609 Fixation of Elastomer to Rigid Structures 8 2006
* 2007/0032,874 Elastomeric intervertebral disc prosthesis 11 2006
8,814,938 Intervertebral disc replacement and associated instrumentation 0 2006
* 2008/0046,082 INTERVERTEBRAL DISC AND NUCLEUS PROSTHESIS 17 2007
9,011,542 Intervertebral prosthesis endplate having double dome and surgical tools for implanting same 0 2007
8,470,045 Endplate for an intervertebral prosthesis and prosthesis incorporating the same 0 2009
* 2011/0060,416 ENDPLATE FOR AN INTERVERTEBRAL PROSTHESIS AND PROSTHESIS INCORPORATING THE SAME 0 2009
9,277,930 Intervertebral disc replacement and associated instrumentation 0 2014
 
GME Delaware 2 LLC (1)
7,955,390 Method and apparatus for spine joint replacement 12 2008
 
DEPUY SYNTHES PRODUCTS, LLC (8)
8,579,908 Device for delivering viscous material 1 2004
8,333,773 Remotely-activated vertebroplasty injection device 9 2007
8,950,929 Fluid delivery system 2 2007
8,540,722 Methods, materials and apparatus for treating bone and other tissue 7 2009
8,361,078 Methods, materials and apparatus for treating bone and other tissue 11 2009
8,809,418 Methods, materials and apparatus for treating bone and other tissue 3 2013
8,956,368 Methods, materials and apparatus for treating bone and other tissue 2 2013
8,992,541 Hydraulic device for the injection of bone cement in percutaneous vertebroplasty 0 2013
 
NEXGEN SPINE, INC. (1)
* 2006/0276,800 Intervertebral disc replacement and surgical instruments therefor 6 2006
 
NEXGEN SPINE, LLC (1)
* 2005/0015,150 Intervertebral disk and nucleus prosthesis 71 2004
 
RAYMEDICA, LLC (4)
* 6,022,376 Percutaneous prosthetic spinal disc nucleus and method of manufacture 426 1998
* 6,602,291 Prosthetic spinal disc nucleus having a shape change characteristic 120 1999
* 6,110,210 Prosthetic spinal disc nucleus having selectively coupled bodies 267 1999
6,533,817 Packaged, partially hydrated prosthetic disc nucleus 156 2000
 
DATUM BIOTECH LTD. (1)
* 2004/0010,251 Methods, devices, and preparations for intervertebral disc treatment 41 2002
 
ZIMMER SPINE AUSTIN, INC. (1)
* 2008/0045,949 Method of treating degenerative spinal disorders 30 2006
 
ARTICULINX, INC. (7)
* 2008/0255,664 PERCUTANEOUSLY DELIVERABLE ORTHOPEDIC JOINT DEVICE 16 2007
* 2008/0255,501 PERCUTANEOUS DELIVERY AND RETRIEVAL SYSTEMS FOR SHAPE-CHANGING ORTHOPEDIC JOINT DEVICES 7 2008
* 2009/0012,612 DEVICES AND METHODS FOR PUSH-DELIVERY OF IMPLANTS 12 2008
* 2011/0029,094 RETRIEVAL OF ORTHOPEDIC JOINT DEVICE 5 2010
* 8,292,954 Disc-based orthopedic devices 2 2010
* 2011/0224,790 DISC-BASED ORTHOPEDIC DEVICES 3 2010
8,764,830 Disc-shaped orthopedic devices 1 2012
 
ABBOTT SPINE, INC. (1)
* 2004/0133,278 Spinal disc implant 107 2003
 
EDWARDS LIFESCIENCES CORPORATION (5)
* 7,871,435 Anatomically approximate prosthetic mitral heart valve 18 2005
* 2006/0293,745 Anatomically approximate prosthetic mitral heart valve 55 2005
8,034,104 Anatomically approximate prosthetic mitral valve 5 2010
* 8,721,716 Prosthetic heart valve with dissimilar leaflets 0 2011
* 2012/0123,530 PROSTHETIC HEART VALVE WITH DISSIMILAR LEAFLETS 8 2011
 
ZIMMER SPINE, INC. (11)
* 2003/0208,274 Pseudo arthrosis device 14 2001
7,112,223 Pseudo arthrosis device 15 2002
* 2003/0229,397 Pseudo arthrosis device 14 2002
* 2007/0093,906 Nucleus implant and method 51 2005
7,645,301 Devices and methods for disc replacement 13 2006
7,534,268 Devices and methods for disc replacement 32 2006
7,905,922 Surgical implant suitable for replacement of an intervertebral disc 7 2006
D566842 Spinal implant 4 2007
8,192,492 Spinal implant 3 2007
* 2008/0200,985 SPINAL IMPLANT 1 2007
8,568,484 Spinal implant 3 2012
 
Zimmer Orthobiologics, Inc. (1)
* 2007/0003,525 Hydrogel compositions comprising nucleus pulposus tissue 8 2004
 
Dr. H.C. Robert Mathys Stiftung (2)
* 8,968,403 Implant device 0 2009
* 2011/0166,659 Implant Device 0 2009
 
GEORGIA TECH RESEARCH CORPORATION (7)
8,002,830 Surface directed cellular attachment 6 2005
7,910,124 Load bearing biocompatible device 6 2005
8,142,808 Method of treating joints with hydrogel implants 5 2008
7,682,540 Method of making hydrogel implants 37 2008
8,318,192 Method of making load bearing hydrogel implants 3 2008
8,895,073 Hydrogel implant with superficial pores 0 2011
8,486,436 Articular joint implant 1 2012
 
MIMEDX PROCESSING SERVICES, LLC (1)
8,172,902 Spinal interbody spacers 0 2009
 
Keraplast Technologies, Ltd. (4)
6,379,690 Keratin-based hydrogel for biomedical applications and method of production 25 2000
6,849,092 Implantable prosthetic or tissue expanding device 19 2001
6,783,546 Implantable prosthetic or tissue expanding device 175 2001
* 2005/0169,963 Implantable prosthetic or tissue expanding device 8 2005
 
CAUTHEN RESEARCH GROUP, INC. (1)
7,670,379 Spinal disc annulus reconstruction method 26 2006
 
TranS1 Inc. (7)
7,717,958 Prosthetic nucleus apparatus 12 2004
7,547,324 Spinal mobility preservation apparatus having an expandable membrane 54 2004
7,491,236 Dual anchor prosthetic nucleus apparatus 64 2004
* 2005/0113,928 Dual anchor prosthetic nucleus apparatus 131 2004
* 2005/0113,929 Spinal mobility preservation apparatus 126 2004
7,905,905 Spinal mobility preservation apparatus 8 2007
7,905,908 Spinal mobility preservation method 11 2007
 
DREXEL UNIVERSITY (1)
* 7,214,245 Associating hydrogels for nucleus pulposus replacement in intervertebral discs 40 2000
 
SMED-TA/TD, LLC (4)
* 2010/0042,218 ORTHOPAEDIC IMPLANT WITH POROUS STRUCTURAL MEMBER 7 2009
* 2010/0042,213 DRUG DELIVERY IMPLANTS 5 2009
* 2010/0042,214 DRUG DELIVERY IMPLANTS 9 2009
* 2010/0042,215 ORTHOPAEDIC IMPLANT 13 2009
 
QUEEN'S UNIVERSITY AT KINGSTON (2)
8,070,777 Method and device for treating abnormal curvature of a spine 1 2008
* 2008/0287,996 Method and device for treating scoliosis 20 2008
 
ST. FRANCIS MEDICAL TECHNOLOGIES, INC. (1)
* 2006/0200,137 Method and device for treating ailments of the spine 73 2006
 
SDGI HOLDINGS, INC. (6)
6,881,228 Artificial disc implant 104 2002
* 6,893,466 Intervertebral disc nucleus implants and methods 150 2002
* 2003/0199,738 Clamping apparatus and methods 12 2003
* 2006/0089,719 In situ formation of intervertebral disc implants 170 2004
* 2005/0096,746 Instrumentation and associated methods for joint prosthesis implantation 5 2004
* 2005/0154,463 Spinal nucleus replacement implants and methods 97 2005
 
RIVERBEND DESIGN LLC (3)
7,201,776 Artificial intervertebral disc replacements with endplates 60 2002
* 2003/0074,076 Artificial intervertebral disc replacements with endplates 45 2002
* 2006/0106,381 Methods and apparatus for treating spinal stenosis 270 2005
 
STRYKER SPINE (2)
6,395,032 Intervertebral disc prosthesis with liquid chamber 255 2001
6,733,532 Intervertebral disc prosthesis with improved mechanical behavior 180 2001
 
P TECH, LLC. (17)
9,155,544 Robotic systems and methods 0 2002
9,138,222 Method and device for securing body tissue 0 2004
9,173,647 Tissue fixation system 0 2006
9,089,323 Device and method for securing body tissue 0 2006
8,747,439 Method of using ultrasonic vibration to secure body tissue with fastening element 1 2006
8,617,208 Method of using ultrasonic vibration to secure body tissue with fastening element 0 2006
9,067,362 Method of using ultrasonic vibration to secure body tissue with fastening element 0 2007
8,617,185 Fixation device 7 2008
8,496,657 Methods for utilizing vibratory energy to weld, stake and/or remove implants 9 2008
9,060,767 Tissue fastener and methods for using same 1 2009
9,173,650 Methods and devices for trauma welding 0 2011
9,192,395 Robotic fastening system 0 2013
9,149,281 Robotic system for engaging a fastener with body tissue 0 2013
9,271,741 Robotic ultrasonic energy system 0 2013
9,271,779 Methods of using a robotic spine system 0 2013
9,226,828 Devices and methods for stabilizing tissue and implants 0 2013
9,271,766 Devices and methods for stabilizing tissue and implants 0 2013
 
FACET SOLUTIONS, INC. (2)
* 2005/0080,486 Facet joint replacement 73 2003
* 2005/0027,361 Facet arthroplasty devices and methods 182 2004
 
KRT INVESTORS, INC. (35)
6,579,291 Devices and methods for the treatment of spinal disorders 224 2000
6,592,625 Spinal disc annulus reconstruction method and spinal disc annulus stent 175 2001
6,689,125 Devices and methods for the treatment of spinal disorders 113 2002
6,835,205 Devices and methods for the treatment of spinal disorders 400 2002
7,052,516 Spinal disc annulus reconstruction method and deformable spinal disc annulus stent 72 2002
7,004,970 Methods and devices for spinal disc annulus reconstruction and repair 108 2002
6,984,247 Spinal disc annulus reconstruction method and spinal disc annulus stent 52 2003
* 2003/0120,345 Spinal disc annulus reconstruction method and spinal disc annulus stent 7 2003
6,805,695 Devices and methods for annular repair of intervertebral discs 257 2003
7,189,235 Spinal disc annulus reconstruction method and spinal disc annulus stent 78 2003
7,033,395 Spinal disc annulus reconstruction method and spinal disc annulus stent 39 2003
6,997,956 Spinal disc annulus reconstruction method and spinal disc annulus stent 42 2003
* 2003/0187,507 Spinal disc annulus reconstruction method and spinal disc annulus stent 6 2003
7,753,941 Devices and methods for annular repair of intervertebral discs 24 2004
7,935,147 Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus 10 2005
8,048,160 Intervertebral disc annulus stent 4 2005
7,828,850 Methods and devices for spinal disc annulus reconstruction and repair 59 2006
8,088,165 Spinal disc annulus reconstruction method and deformable spinal disc annulus stent 4 2006
8,632,590 Apparatus and methods for the treatment of the intervertebral disc 6 2006
7,985,257 Methods and devices for spinal disc annulus reconstruction and repair 8 2006
7,909,879 Intervertebral disc annulus stent 11 2006
7,922,768 Spinal disc annulus reconstruction method and deformable spinal disc annulus stent 14 2006
7,993,405 Spinal disc annulus repair system and methods 7 2006
7,951,201 Method and apparatus for the treatment of the intervertebral disc annulus 11 2007
7,749,273 Method and apparatus for the treatment of the intervertebral disc annulus 72 2007
7,905,923 Devices and methods for annular repair of intervertebral discs 5 2007
8,128,698 Method and apparatus for the treatment of the intervertebral disc annulus 8 2008
8,163,022 Method and apparatus for the treatment of the intervertebral disc annulus 3 2009
8,652,153 Intervertebral disc annulus repair system and bone anchor delivery tool 0 2010
8,460,319 Intervertebral disc annulus repair system and method 0 2010
8,556,977 Tissue anchoring system and method 5 2010
9,114,025 Methods and devices for spinal disc annulus reconstruction and repair 0 2011
9,095,442 Method and apparatus for the treatment of the intervertebral disc annulus 0 2012
8,454,697 Method and apparatus for the treatment of tissue 4 2012
9,192,372 Method for the treatment of tissue 0 2013
 
Doctors Research Group, Inc. (1)
* 2011/0015,743 MULTI-DENSITY POLYMERIC INTERBODY SPACER 1 2009
 
DISC DYNAMICS, INC. (6)
* 6,224,630 Implantable tissue repair device 471 1998
7,077,865 Method of making an intervertebral disc prosthesis 100 2003
7,001,431 Intervertebral disc prosthesis 181 2003
* 2003/0195,628 Method of making an intervertebral disc prosthesis 40 2003
7,713,301 Intervertebral disc prosthesis 27 2006
7,766,965 Method of making an intervertebral disc prosthesis 51 2006
 
CARTIVA, INC (1)
9,155,543 Tapered joint implant and related tools 0 2012
 
BONUTTI SKELETAL INNOVATIONS LLC (4)
8,814,902 Method of securing body tissue 2 2006
8,845,699 Method of securing tissue 2 2012
8,808,329 Apparatus and method for securing a portion of a body 0 2012
8,845,687 Anchor for securing a suture 0 2013
 
Ortho Development Corporation (9)
6,579,318 Intervertebral spacer 177 2000
6,852,127 Method of implanting an intervertebral spacer 20 2002
* 2002/0065,560 Intervertebral spacing implant system 44 2002
D501555 Implant 36 2003
D494274 Implant 38 2003
D493225 Implant 40 2003
* 2004/0186,574 Intervertebral spacing implant system 12 2004
* 2004/0186,575 Method of implanting an intervertebral spacer 14 2004
* 2006/0212,119 Intervertebral spacer 10 2006
 
DEPUY SPINE, INC. (1)
8,066,713 Remotely-activated vertebroplasty injection device 16 2003
 
VALVE HOLDINGS, L.L.C. (1)
6,758,863 Vertically expanding intervertebral body fusion device 152 2002
 
MEDICINELODGE, INC. DBA IMDS CO-INNOVATION (5)
6,579,319 Facet joint replacement 333 2000
6,565,605 Multiple facet joint replacement 351 2000
6,419,703 Prosthesis for the replacement of a posterior element of a vertebra 347 2001
7,090,698 Method and apparatus for spine joint replacement 186 2002
* 2003/0004,572 Method and apparatus for spine joint replacement 51 2002
 
GORENSEK, BOGOMIR, MR (2)
7,201,775 Stabilizing device for intervertebral disc, and methods thereof 53 2003
* 2004/0230,305 Stabilizing device for intervertebral disc, and methods thereof 4 2003
 
SPINEMEDICA, LLC (3)
* 2007/0191,957 SPINAL IMPLANTS WITH COOPERATING SUTURE ANCHORS 4 2007
* 2007/0164,464 FLEXIBLE SPINAL DISC 8 2007
* 2008/0004,702 SPINAL IMPLANTS WITH COOPERATING ANCHORING SUTURES 4 2007
 
Transl, Inc. (2)
7,662,173 Spinal mobility preservation apparatus 55 2004
7,329,259 Articulating spinal implant 69 2004
 
PEARSALLS, LTD. (1)
* 2008/0306,595 Porous Implant For Spinal Disc Nucleus Replacement 6 2005
 
Collabcom II, LLC (2)
8,202,299 Interspinous implant, tools and methods of implanting 6 2008
8,721,688 Interspinous implant, tools and methods of implanting 0 2012
 
SpinLabs, LLC (1)
* 6,402,750 Devices and methods for the treatment of spinal disorders 589 2000
 
Pioneer Signal Technology, Inc. (1)
8,388,684 Artificial disc device 9 2003
 
DEPUY SYNTHES PRODUCTS, INC. (4)
8,415,407 Methods, materials, and apparatus for treating bone and other tissue 8 2006
8,360,629 Mixing apparatus having central and planetary mixing elements 7 2006
9,259,696 Mixing apparatus having central and planetary mixing elements 0 2012
9,186,194 Hydraulic device for the injection of bone cement in percutaneous vertebroplasty 0 2015
 
LAWSON, KEVIN J., AN INDIVIDUAL (1)
* 6,146,422 Prosthetic nucleus replacement for surgical reconstruction of intervertebral discs and treatment method 237 1999
 
ANOVA CORP. (27)
6,419,704 Artificial intervertebral disc replacement methods and apparatus 491 1999
6,454,804 Engineered tissue annulus fibrosis augmentation methods and apparatus 113 2000
6,969,404 Annulus fibrosis augmentation methods and apparatus 129 2002
6,793,677 Method of providing cells and other biologic materials for transplantation 39 2002
* 2002/0128,630 Method and apparatus for providing nutrition to intervertebral disc tissue 1 2002
6,755,863 Rotator cuff repair using engineered tissues 13 2002
* 2004/0093,092 Rotator cuff repair using engineered tissues 1 2002
6,648,919 Transplantation of engineered meniscus tissue to the intervertebral disc 75 2002
6,648,920 Natural and synthetic supplements to engineered annulus and disc tissues 79 2002
* 2002/0151,981 Transplantation of engineered meniscus tissue to the intervertebral disc 4 2002
* 2004/0172,019 Reinforcers for artificial disc replacement methods and apparatus 12 2002
* 7,201,774 Artificial intervertebral disc replacements incorporating reinforced wall sections 22 2003
6,875,235 Prosthetic joints with contained compressible resilient members 48 2003
* 2005/0261,773 Lateral-approach artificial disc replacements 29 2003
7,273,497 Methods for treating a defect in the annulus fibrosis 51 2003
* 2004/0097,980 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft 28 2003
* 2004/0186,573 Annulus fibrosis augmentation methods and apparatus 38 2004
7,435,260 Use of morphogenetic proteins to treat human disc disease 29 2004
* 2004/0230,310 Use of morphogenic proteins to treat human disc disease 1 2004
7,060,100 Artificial disc and joint replacements with modular cushioning components 26 2004
9,084,616 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft 0 2006
* 2007/0027,471 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft 21 2006
7,914,553 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft 12 2007
* 2007/0142,839 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft 21 2007
8,821,549 Methods and apparatus for anulus repair 0 2009
8,936,642 Methods for treating a defect in the annulus fibrosis 0 2011
9,232,938 Method and apparatus for closing fissures in the annulus fibrosus 0 2012
 
COLLABCOM5, LLC., A COLORADO LIMITED LIABILITY CORP. (1)
8,974,496 Interspinous implant, tools and methods of implanting 0 2007
 
COLBAR LIFESCIENCE LTD. (1)
* 2008/0026,032 COMPOSITE IMPLANTS FOR PROMOTING BONE REGENERATION AND AUGMENTATION AND METHODS FOR THEIR PREPARATION AND USE 2 2007
 
GLOBUS MEDICAL, INC. (21)
6,974,478 Prostheses, systems and methods for replacement of natural facet joints with artificial facet joint surfaces 210 2002
* 2003/0028,250 Prostheses, systems and methods for replacement of natural facet joints with artifical facet joint surfaces 69 2002
6,902,580 Prosthesis for the replacement of a posterior element of a vertebra 170 2002
7,074,237 Multiple facet joint replacement 149 2003
* 2003/0204,259 Multiple facet joint replacement 38 2003
7,041,136 Facet joint replacement 223 2003
* 2003/0191,532 Facet joint replacement 38 2003
7,074,238 Prostheses, tools and methods for replacement of natural facet joints with artificial facet joint surfaces 72 2003
* 2005/0010,291 Prostheses, tools and methods for replacement of natural facet joints with artificial facet joint surfaces 34 2003
7,087,084 Method for replacing a natural facet joint with a prosthesis having an artificial facet joint structure 143 2003
* 2004/0111,154 Facet arthroplasty devices and methods 29 2003
* 2005/0235,508 Facet joint prosthesis measurement and implant tools 9 2004
7,753,937 Linked bilateral spinal facet implants and methods of use 27 2004
7,588,590 Spinal facet implant with spherical implant apposition surface and bone bed and methods of use 26 2004
7,674,296 Expandable vertebral prosthesis 35 2005
* 2008/0287,959 MEASUREMENT AND TRIALING SYSTEM AND METHODS FOR ORTHOPEDIC DEVICE COMPONENT SELECTION 7 2008
8,333,789 Facet joint replacement 0 2008
* 2008/0292,161 IMPLANTABLE ORTHOPEDIC DEVICE COMPONENT SELECTION INSTRUMENT AND METHODS 18 2008
7,815,648 Surgical measurement systems and methods 1 2008
8,721,723 Expandable vertebral prosthesis 4 2009
8,282,683 Expandable vertebral implant 5 2010
 
CORTEK SPINE, INC. (1)
6,241,769 Implant for spinal fusion 234 1998
 
Spinadyne, Inc. (1)
D598105 Convex intervertebral disc prosthesis 2 2008
 
Spine Wave, Inc. (2)
* 7,806,914 Dynamic spinal stabilization system 29 2003
* 2005/0143,823 Dynamic spinal stabilization system 167 2003
 
Gmedelware 2 LLC (1)
8,926,700 Spinal facet joint implant 0 2004
* Cited By Examiner