Retinoid-based compositions and method for preventing adhesion formation using the same
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United States of America Patent
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Jul 9, 1996
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N/A
app pub date -
Jan 17, 1995
filing date -
Jan 17, 1995
priority date (Note) -
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Abstract
Compositions and methods for prevention of adhesion formation, whereby an effective amount of at least one retinoid, e.g., all trans retinoic acid, is administered for a period of time sufficient to permit tissue repair. The retinoid is preferably administered in conjunction with a delivery vehicle (e.g., microcapsules, microspheres, biodegradable polymer films, lipid-based delivery systems such as liposomes and lipid foams, viscous instillates and absorbable mechanical barriers) useful for maintaining local concentrations of the compound at the injury site at an effective level.
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