Monoclonal antibody specific for vascular endothelial cell antigen endoglyx-1 and uses thereof for detection of, and isolation of, vascular endothelial cells

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United States of America Patent

PATENT NO 5536641
SERIAL NO

08243288

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Abstract

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An antigen which is specific to vascular endothelium is described. Described is a cell surface antigen which consists of four subunits, of 190, 145, 125 and 110 kd as determined by SDS-PAGE under reducing conditions as is a monoclonal antibody specific to this antigen. Uses, both diagnostic and therapeutic, are also described.

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Patent Owner(s)

Patent OwnerAddress
MEMORIAL SLOAN KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK NY 10065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Garin-Chesa, Pilar Biberach, DE 35 469
Old, Lloyd J New York, NY 146 1803
Rettig, Wolfgang J Biberach, DE 20 337
Sanz-Moncasi, Maria P Zaragoza, ES 2 5
Stockert, Elisabeth New York, NY 36 438

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