Integrin-binding peptides

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United States of America Patent

PATENT NO 5536814
SERIAL NO

08212186

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Abstract

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The present invention provides peptides having specificity for fibronectin-binding and vitronectin-binding integrins, and in particular for .alpha..sub.5 .beta..sub.1 integrin. These peptides are characterized by having the ability to interfere with extracellular matrix protein binding to integrins; to block attachment of cells expressing these integrins to extracellular matrix proteins; and to promote cell attachment when coated onto a surface.

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Patent Owner(s)

Patent OwnerAddress
BEHRING DIAGNOSTICS GMBHEMIL-VON-BEHRINGSTRASSE 76 35001 MARBURG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koivunen, Erkki San Diego, CA 20 648
Ruoslahti, Erkki Rancho Sante Fe, CA 118 2392

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