Detection of type II collagen and its peptides
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United States of America Patent
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Jul 30, 1996
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app pub date -
Feb 12, 1993
filing date -
Feb 12, 1993
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Abstract
The invention discloses monoclonal antibodies which bind specifically to Type II collagen, but not to its peptides, or vice versa. Also disclosed are the methods of preparing hybridomas for production of these antibodies; the assays which utilize these antibodies to detect or quantify Type II collagen and/or its peptides in a solution (e.g., body fluid, culture medium, and tissue extract); and assay kits containing these antibodies.
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