Heterocyclic derivatives in the treatment of ischaemia and related diseases
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United States of America Patent
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Aug 13, 1996
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N/A
app pub date -
Mar 9, 1995
filing date -
Apr 9, 1993
priority date (Note) -
Expired
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Abstract
Compounds of the formula: ##STR1## wherein: m is 0 or 1; R.sup.1 is hydrogen, hydroxy, or lower alkyl; R.sup.2 is hydrogen, or lower alkyl; R.sup.3 is ##STR2## or R.sup.2 and R.sup.3 taken together with the nitrogen atom to which they are attached represent a group of the formula: ##STR3## wherein: n is 0 or 1; p is 0, 1, 2 or 3; q is 0 or 1; R.sup.4 is hydrogen, lower alkyl, cycloalkyl, or optionally substituted phenyl; R.sup.5 is optionally substituted phenyl; X is (CH.sub.2).sub.p, or 4-piperidin-1-yl; Y is CH, CH--O--, CH--S--, or nitrogen; Z is CH.sub.2, NH, sulfur, or oxygen; and A is a substituted furanyl group.
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