Expression of recombinant proteins in attenuated bacteria
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United States of America Patent
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Aug 20, 1996
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app pub date -
Dec 12, 1994
filing date -
Mar 5, 1991
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Abstract
The invention concerns a vaccine comprising an attenuated Salmonella bacterium which contains a nirB promoter operably linked to a DNA sequence encoding a heterologous protein. The nirB promoter directs expression of the heterologous protein in a host it is wished to vaccinate.
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