Multilayer matrix systems for the controlled release of active principles
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United States of America Patent
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Aug 27, 1996
Grant Date -
N/A
app pub date -
Nov 16, 1993
filing date -
Nov 17, 1992
priority date (Note) -
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Abstract
This invention concerns systems for the release of active principles which are capable of releasing active principle(s) into an aqueous medium at a controlled rate. More precisely, the invention concerns a monolithic system for the controlled release of active principles, consisting of: a) at least one swelling layer containing one or more active principles, in a matrix of swellable, hydrophilic polymers; b) at least one erodible and/or soluble layer comprising excipients and/or water soluble polymers, possibly containing one or more active principles, either the same or different from those present in the layer a), the said erodible and/or soluble layer being in contact with the swelling layer(s) a).
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