.DELTA..sup.6,7 -taxols antineoplatic use and pharmaceutical compositions containing them

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United States of America Patent

PATENT NO 5556878
SERIAL NO

08258019

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Abstract

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This invention provides 7-deoxy-.DELTA..sup.6,7 -taxol and 7-deoxy-.DELTA..sup.6,7 -taxol analogs of Formula I: ##STR1## The compounds of Formula I are useful for the same cancers for which taxol has been shown active, including human ovarian cancer, breast cancer, and malignant melanoma as well as lung cancer, gastric cancer, colon cancer, head and neck cancer, and leukemia.

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Patent Owner(s)

Patent OwnerAddress
THE UPJOHN COMPANYKALAMAZOO MICHIGAN 49001

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Johnson, Roy A Kalamazoo, MI 78 366
Kelly, Robert C Augusta, MI 46 350
Nidy, Eldon G Kalamazoo, MI 2 33
Skulnick, Harvey I Kalamazoo, MI 18 149

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