Linear aminoalkylphosphoramidate oligonucleotide derivatives
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United States of America Patent
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Oct 8, 1996
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app pub date -
Mar 3, 1994
filing date -
Mar 8, 1990
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Abstract
Disclosed are methods of producing a synthetic oligonucleotide of selected nucleotide sequence which is internally functionalized at at least one selected location with an aminoalkyl-phosphoramidate and labelled with a nonradioactive material. Also disclosed are oligonucleotides produced by this method.
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