Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs

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United States of America Patent

PATENT NO 5565478
SERIAL NO

08212612

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Abstract

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The present invention provides compositions and methods for the treatment of cancer in a subject wherein compounds of formula I defined herein in combination with paclitaxel or other modified taxane analogs provide enhanced anticancer effects over the effects achieved with the individual compounds.

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Patent Owner(s)

Patent OwnerAddress
UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICESNATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY TRANSFER 6011 EXECUTIVE BLVD STE 325 ROCKVILLE MD 20852 ROCKVILLE MD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kohn, Elise C Olney, MD 14 201
Liotta, Lance A Potomac, MD 104 1525
Reed, Eddie Germantown, MD 14 120

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