Stable microbubbles suspensions injectable into living organisms

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United States of America Patent

PATENT NO 5567414
SERIAL NO

08457581

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophillc stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.

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Patent Owner(s)

  • BRACCO INTERNATIONAL B.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bichon, Daniel Montpellier, FR 54 1965
Bussat, Philippe Collonges S/Saleve, FR 91 1928
Hybl-Sutherland, Eva Wiesbaden, DE 8 979
Puginier, Jerome Le Chable-Beaumont, FR 44 1745
Schneider, Michel Troinex, CH 119 3778

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