Vaccine delivery system for immunization, using biodegradable polymer microspheres

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 5569468
SERIAL NO

08197754

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A controlled release oral formulation, for human vaccines, are formed in microspherical form. The vaccine is suspended in a polymer matrix. The polymer matrix is formed from at least two highly water soluble biodegradable polymers, selected for example from starch, crosslinked starch, ficoll, polysucrose, polyvinyl alcohol, gelatine, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl-ethyl cellulose, hydroxypropyl-methyl cellulose, sodium carboxymethyl cellulose, cellulose acetate, sodium alginate, polymaleic anhydride esters, polyortho esters, polyethyteneimine, polyethylene glycol, methoxypolyethylene glycol, ethoxypolyethylene glycol, polyethylene oxide,poly(1,3 bis(p-carboxyphenoxy) propane-co-sebacic anhydride, N,N-diethylaminoacetate, block copolymers of polyoxyethylene and polyoxypropylene. The microspheres are coated with a (d,1 lactide-glycolide) copolymer. The coating makes the microspheres more resistant to enzymatic degradation.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
CENTRUM BIOTECHNOLOGIES INC.BURLINGTON ONT, CA2

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Modi, Pankaj 1928 Main St. W. Apt. 608, Hamilton, CA 46 855

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
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SYNTEX (U.S.A.) INC. (1)
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UNIVERSITY OF WASHINGTON (1)
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DEBIO RECHERCHE PHARMACEUTIQUE S.A. (4)
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TCF NATIONAL BANK (1)
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Patent Citation Ranking

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Other [Check patent profile for assignment information] (1)
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9463426 Methods and systems for coating particles 0 2005
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WILLIAM MARSH RICE UNIVERSITY (3)
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TIF MANAGEMENT, LLC (1)
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* Cited By Examiner