Fully integrated miniaturized planar liquid sample handling and analysis device
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United States of America Patent
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Nov 5, 1996
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N/A
app pub date -
Jun 7, 1995
filing date -
Oct 19, 1994
priority date (Note) -
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Abstract
A miniaturized total analysis system ('.mu.-TAS') comprising a miniaturized planar column device is described for use in liquid phase analysis. The .mu.-TAS comprises microstructures fabricated by laser ablation in a variety of novel support substrates. The .mu.-TAS includes associated laser-ablated features required for integrated sample analysis, such as analyte detection means and fluid communication means. .mu.-TAS constructed according to the invention is useful in any analysis system for detecting and analyzing small and/or macromolecular solutes in the liquid phase and may employ chromatographic separation means, electrophoretic separation means, electrochromatographic separation means, or combinations thereof.
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