Methods and materials for detecting autoimmune antibodies

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United States of America Patent

PATENT NO 5573911
SERIAL NO

08330147

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The subject invention pertains to a method of binding proteins and double-stranded DNA to the same membrane matrix. The DNA bound to the membrane matrix remains in double-stranded form. The subject invention further concerns an assay procedure for detecting antibodies, such as autoimmune antibodies, in a biological sample that are immunoreactive with the proteins and double-stranded DNA attached to a membrane matrix. The subject invention provides a single assay system that allows for the determination of antinuclear antibody specificities which can be used to aid in the diagnosis and monitoring of autoimmune diseases.

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Patent Owner(s)

Patent OwnerAddress
TEPNEL LIFECODES CORPORATION550 WEST AVENUE STAMFORD CT 06902

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Pieti, Lisa M Norwalk, CT 1 2
Victor, Jacob Passaic, NJ 3 3

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