Production of chimeric mouse-human antibodies with specificity to human tumor antigens

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United States of America Patent

PATENT NO 5576184
SERIAL NO

08364001

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Abstract

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Gene expression elements and their use in production of chimeric antibodies with human constant regions and murine variable regions, and mouse human chimeric antibodies having specificity to human tumor cells, methods of their production, and their use.

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Patent Owner(s)

  • XOMA CORPORATION;XOMA TECHNOLOGY LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Better, Marc D Los Angeles, CA 27 480
Chang, Changtung P Chatsworth, CA 2 200
Horwitz, Arnold H Los Angeles, CA 27 1156
Lei, Shau-Ping Los Angeles, CA 16 1231
Robinson, Randy R Los Angeles, CA 22 2367

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