Method and composition for optimizing left ventricular videointensity in echocardiography
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United States of America Patent
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Nov 26, 1996
Issued Date -
N/A
app pub date -
Sep 6, 1994
filing date -
May 14, 1993
priority date (Note) -
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Abstract
This invention provides a new ultrasound contrast agent which is safe and can reach the left side of the heart in adequate amounts to determine blood flow to the muscle of the heart. The contrast agent comprises a simple sonicated mixture of a protein the body normally makes (albumin) combined with a naturally occurring sugar (dextrose). This mixture upon sonication contains small bubbles (microbubbles) and can be used following an intravenous injection to study blood flow to the muscle of the heart (myocardium) without the need of invasive catheters or radiation. In another embodiment, there is provided an inexpensive test to study blood flow in the heart using echocardiography, thus avoiding the more expensive nuclear procedures that are presently employed to determine blood flow in the heart muscle, and eliminating the risk of radiation.
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