Substantially pure receptor like TFG-.beta.1 binding molecules
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United States of America Patent
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Nov 26, 1996
Issued Date -
N/A
app pub date -
Apr 22, 1994
filing date -
Jun 18, 1991
priority date (Note) -
Expired
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Abstract
The invention relates to a family of substantially pure, receptor like TGF-.beta.1 binding glycoproteins. These molecules are characterized by molecular masses of 160 kd, 70-80 kd, and 30-40 kd as determined by SDS-PAGE, and the ability to bind the TGF-.beta.1 molecule. This family of molecules is useful in identifying and/or quantifying TGF-.beta.1 in a sample, as well as inhibiting its effect on cells. Also described are nucleic acid sequences which code for the protein monomer making up the molecules.
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