Thiol-derivatized nucleosides
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United States of America Patent
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Nov 26, 1996
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N/A
app pub date -
Sep 3, 1993
filing date -
Jan 11, 1990
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Abstract
Nucleosides and linked nucleosides functionalized to include alkylthiol chemical functionality at ribofuranosyl positions, nucleosidic base positions, or on internucleoside linkages. In certain embodiments, the compounds of the invention further include steroids, reporter molecules, reporter enzymes, lipophilic molecules, peptides or proteins attached to the nucleosides through the alkylthio group.
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