Delivery of exogenous DNA sequences in a mammal

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United States of America Patent

PATENT NO 5580859
SERIAL NO

08215405

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Polynucleotide sequences, comprising DNA and RNA molecules can be directly administered, for example by injection, to tissues, such as muscle, and expressed as a protein, polypeptide or polypeptide. The polynucleotides can be contained within liposomes or the polynucleotides can free from association with transfection-facilitating proteins, viral particles, liposomal formulations, charged lipids and calcium phosphate precipitating agents.

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Patent Owner(s)

  • VICAL INCORPORATED;WISCONSIN ALUMNI RESEARCH FOUNDATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carson, Dennis A Del Mar, CA 115 5320
Felgner, Philip L Rancho Santa Fe, CA 49 5882
Malone, Robert W Chicago, IL 9 1981
Rhodes, Gary H Leucadia, CA 13 2913
Wolff, Jon A Madison, WI 140 4996

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