Substituted thioureas as bifunctional chelators
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United States of America Patent
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Dec 17, 1996
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app pub date -
Jun 27, 1994
filing date -
Apr 9, 1992
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Abstract
This invention relates to chelating agents useful for coupling metal ions to biologically active molecules. In particular, substantial thioureas for chelating metals such as technetium are provided that can be conjugated to a targeting molecule such as an antibody, a peptide or a protein.
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