Inhibitors of poly(ADP-ribose) synthetase and use thereof to treat NMDA neurotoxicity

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Dec 24, 1996
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Feb 4, 1994
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Feb 4, 1994

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Abstract

Inhibitors of poly(ADP-ribose) synthetase can be used to prevent neurotoxicity mediated through N-methyl-D-aspartate (NMDA) receptors. Poly(ADP-ribose) synthetase inhibitors can be used therapeutically in the treatment of vascular stroke and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and Huntington's disease.

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Patent Owner	Address
UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES	C/O NATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY TRANSFER BOX OTT BETHESDA MD 20892

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A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....

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Inventor Name	Address	# of filed Patents	Total Citations
Dawson, Ted M	Baltimore, MD	26	248
Dawson, Valina L	Baltimore, MD	20	216
Snyder, Solomon H	Baltimore, MD	48	772
Zhang, Jie	Baltimore, MD	1052	8750

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Inhibitors of poly(ADP-ribose) synthetase and use thereof to treat NMDA neurotoxicity

Number of patents in Portfolio can not be more than 2000

United States of America Patent

08191508

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SERIAL NO	08191508
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