Methods and agents for the prophylaxis of atopy
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United States of America Patent
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Jan 7, 1997
Issued Date -
N/A
app pub date -
Apr 11, 1995
filing date -
Apr 4, 1989
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A method for atopy prophylaxis involves administering an agent comprising .gamma.-linolenic acid, dihomo-.gamma.-linolinic acid, the physiologically compatible salts, esters, amides, phospholipids, glycolipids thereof, and/or prostaglandin E.sub.1 (PGE.sub.1), PGE.sub.1 derivatives, PGE.sub.1 analogs to preimmunocompetent humans to prevent the occurrence of atopy. These agents are typically contained in a baby food or are supplied to the baby concurrently. These foods may contain one or more thymus hormones. The use of PGE.sub.1, its derivatives and analogs and the physiologically compatible esters, amides, phospholipids and glycolipids thereof in a pharmacologically effective dosage form for the topical or inhalative treatment of acute manifest atopy in the dermal and mucosal areas. These substances are preferably used in combination with .gamma.-linolinic acid, and dihomo-.gamma.-linolinic acid, and/or the physiologically compatible salts, esters, amides, phospholipids and glycolipids thereof.
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