Chromophore probe for detection of nucleic acid
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United States of America Patent
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Jan 21, 1997
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jan 21, 1992
priority date (Note) -
Expired
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Abstract
The present invention is directed to chromophoric probes for use in detecting nucleic acid sequences. More particularly, the invention is directed to probes that comprise a texaphyrin chromophore molecule covalently coupled or conjugated to a site-directing molecule, the site-directing molecule having affinity for a biological receptor or a nucleic acid sequence. In one embodiment of the invention, the probe comprises a texaphyrin chromophore conjugated to an oligonucleotide having complementary binding affinity for a target nucleic acid sequence.
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