US Patent No: 5,597,570

Number of patents in Portfolio can not be more than 2000

Protein recognized by antibodies raised against native P28 of schistosoma mansoni

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Abstract

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The present invention relates to the development of a vaccine against schistosomiasis. It relates to a protein which includes the epitopes of the p28 protein, a poxvirus containing a gene coding for the said protein, a cell incorporating a vector for the expression of the said protein, a method for preparing the said protein, a DNA sequence coding for the p28 protein, a pharmaceutical composition, antibodies raised against the said protein and their application by way of diagnostic agents for schistosomiasis. The present invention also relates to the application of the said protein by way of an agent possessing glutathione S-transferase activity.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
TRANSGENE S.A.STRASBOURG126

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balloul, Jean-Marc Lingolsheim, FR 20 31
Capron, Andre Phalempin, FR 14 29
Grzych, Jean-Marie Marcq en Baroeul, FR 4 17
Kieny, Marie-Paule Strasbourg, FR 20 123
Lecocq, Jean-Pierre Reichstett, FR 12 41
Loison, Gerard Strasbourg, FR 10 37
Pierce, Raymond Seclin, FR 3 7
Sondermeyer, Paul Strasbourg, FR 2 7

Cited Art Landscape

Patent Info (Count) # Cites Year
 
LOWERS, MARK (1)
4,396,600 Adult schistosome worm-derived antigenic substance and method of obtaining same 23 1980
 
The Johns Hopkins University (1)
5,051,254 Immunoprophylactic polypeptides for schistosomiasis 3 1988
 
Other [Check patent profile for assignment information] (1)
4,384,992 Novel peptide from cultures of Schistosoma mansoni, a process for producing it and pharmaceutical compositions containing the same 2 1981

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ACAMBIS RESEARCH LIMITED (1)
6,680,182 Expression of recombinant fusion proteins in attenuated bacteria 1 1995
 
THOMAS JEFFERSON UNIVERSITY (1)
6,475,999 Method of inducing an immune response using vaccinia virus recombinants 1 2000