Hybrid RNA virus
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United States of America Patent
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Feb 11, 1997
Issued Date -
N/A
app pub date -
May 22, 1995
filing date -
Feb 9, 1987
priority date (Note) -
In Force
status (Latency Note)
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Abstract
A recombinant RNA virus is provided allowing encapsidation of genetically engineered viral sequences in heterologous, preferably rod-shaped coat, protein capsids. Since icosahedral viruses are limited in the amount of RNA they can carry, and rod-shaped viruses are expansible, this invention allows the size of recombinant virus RNA components to be increased (or decreased). Methods of making and using such recombinant viruses are also provided, specifically with respect to the transfection of plants to bring about genotypic and phenotypic changes.
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