Liquid core microdroplets for ultrasound imaging
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United States of America Patent
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Mar 4, 1997
Grant Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jun 7, 1995
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Ultrasonic imaging agents comprising an aqueous suspension of negatively buoyant aspherical microdroplets composed of a biocompatible liquid core encapsulated by a shell of amphiphilic biocompatible material are prepared by milling a mixture of a solution of the shell material and vaporized liquid and cooling the milled mixture to below the boiling point of the liquid.
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