Biocompatible medical article and method
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United States of America Patent
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-
Mar 4, 1997
Grant Date -
N/A
app pub date -
Aug 22, 1995
filing date -
Aug 22, 1995
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A medical article having a metal or glass surface with the surface having an adherent coating of improved biocompatibility. The coating is made by first applying to the surface an silane compound having a pendant vinyl functionality such that the silane adheres to the surface and then, in a separate step, forming a graft polymer on the surface with applied vinylsilane such that the pendant vinyl functionality of the vinylsilane is incorporated into the graft polymer by covalent bonding with the polymer. Biomolecules may then be covalently attached to the base layer.
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