DNA photocleavage using texaphyrins
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United States of America Patent
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Mar 4, 1997
Issued Date -
N/A
app pub date -
Jun 6, 1995
filing date -
Jan 21, 1992
priority date (Note) -
Expired
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Abstract
Methods of cleavage of a polymer of deoxyribonucleic acid using photosensitive texaphyrins are disclosed. A preferred method of use is the site-specific cleavage of a polymer of deoxyribonucleic acid and a preferred texaphyrin is a derivatized texaphyrin having binding specificity, in particular, a texaphyrin covalently coupled to a site-directing molecule, preferably an oligonucleotide.
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