Titanium-based bone-bonding composites having inverted concentration gradients of alkali and titanium ions in a surface layer
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United States of America Patent
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Mar 11, 1997
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N/A
app pub date -
Nov 9, 1994
filing date -
Nov 9, 1993
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Abstract
A bone substitute, which provides both the fracture toughness of titanium or titanium alloys and the bioactivity of apatite, wherein titanium or titanium alloys and apatite are tightly adhered, is produced by soaking a substrate of titanium or titanium alloy in an alkaline solution to form a layer comprising amorphous alkali titanate, followed by the heating of the said substrate up to at most the titanium or titanium alloy transition temperature so as to form a stabilized amorphous alkali titanate layer and a sufficient concentration gradient of alkali and titanium ions to permit the growth of apatite thereon from solutions containing apatite-containing ions.
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